4 days · 3 nights · private
A Taste of the Argentine Northwest
Cloud forest, the Quebrada de Humahuaca, the Salinas Grandes, Route 40 and the Cafayate wine valleys in one private loop from Salta.
USD 2,132 for 1 to 4 travellers
Day-by-day itineraryTravel guide · Itinerary
By Pablo Pérez Sancho, tour guide in Salta · Updated October 2026
Two weeks is enough for Argentina's three classic sides: the city in Buenos Aires, the jungle at Iguazú Falls and the Andes in Salta and Jujuy. All three are connected by direct flights, including Iguazú to Salta a few days a week, so you never backtrack. Travelling between April and November, all three are in season.

| Days | Where | What |
|---|---|---|
| 1 to 4 | Buenos Aires | Arrive at Ezeiza, rest, neighbourhoods, a tango show, a parrilla |
| 5 to 7 | Iguazú Falls | Fly from Aeroparque; the Argentine side of the falls, the Brazilian side if you have time |
| 8 to 13 | Salta & Jujuy | Fly direct to Salta; Quebrada de Humahuaca, Salinas Grandes, Cachi, Cafayate |
| 14 | Salta to Buenos Aires | Fly back and connect to your international flight |
Most international flights from the US land at Ezeiza in the morning after an overnight flight. A few days in the city let you recover before the domestic flights, and you can leave Buenos Aires again from Aeroparque, the city airport.
Aerolíneas Argentinas flies direct between Iguazú and Salta a few times a week, about two hours. Build your dates around those days. If they do not fit, connect through Buenos Aires: it adds a few hours but works every day.
Five or six days covers the whole loop: the Quebrada de Humahuaca and El Hornocal, the Salinas Grandes, the Cuesta del Obispo to Cachi, Route 40 and the wine town of Cafayate. Sleeping in Tilcara and Cachi helps with the altitude. Our 5-day itinerary has the details day by day.
With two weeks, swap something rather than add it. For Patagonia, travel in the southern summer and shorten Buenos Aires and Salta. For Mendoza, swap Iguazú, or add three days if you have them. Trying to see everything in two weeks means more time at airports than in the places.
Sources: Flights: Despegar, Skyscanner and Directflights route data, checked in October 2026; confirm schedules with the airline. Seasons and altitudes: as in our other guides.
Travel with Pablo
For the Salta part of your two weeks, Pablo can pick you up at the airport and guide the whole loop, or plan a tailor-made trip that fits your flights.
4 days · 3 nights · private
Cloud forest, the Quebrada de Humahuaca, the Salinas Grandes, Route 40 and the Cafayate wine valleys in one private loop from Salta.
USD 2,132 for 1 to 4 travellers
Day-by-day itineraryWant a different route? Pablo plans tailor-made trips of 3 to 13+ days. How tailor-made trips work
More travel guides: Best time to visit Salta & Jujuy · Altitude sickness in Salta & Jujuy · Self-drive or private guide in Salta · Salta & Jujuy driving distances · El Hornocal guide · Salinas Grandes guide · Cafayate wine guide · Cachi guide · Quebrada de Humahuaca guide · 5-day Salta & Jujuy itinerary · Argentina for US travelers · Buenos Aires to Salta · Is Salta worth visiting?
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